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1-Methyl-4-nitrosopiperazine
N-Methyl-N'-nitrosopiperazine; 1-Nitroso-4-methylpiperazine; N-Nitroso-N'-methylpiperazine
16339-07-4
C5H11N3O
129.16
Inert Gas, 2-8°C
Room Temperature
1-Methyl-4-nitrosopiperazine (MNP) is
primarily used as a pharmaceutical analytical standard, particularly to detect and quantify it as a nitrosamine impurity in drugs like rifampicin, aiding quality control and method development. It's also a research chemical for studying nitrosamine formation and potential carcinogenicity, used in developing analytical methods (LC-MS/MS), and for stability testing in drug R&D, often with labeled isotopes (MNP-d4, MNP-d11). Due to its potential toxicity and carcinogenicity, it requires careful handling.
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